As per kanna information available, it regulates the production of neurotransmitters (dopamine, epinephrine, and nor-epinephrine) from brain by acting as selective serotonin reuptake inhibitor on neuronal terminals. Due to this effect, it acts as a natural antidepressant. Its effect on fertility has much importance. Kanna and how do you prevent postpartum depression influences great effects on male fertility. According to kanna information, it increases the DNA fragmentation in sperm. Due to this DNA fragmentation of sperms, defective sperms are produced and decrease the fertility level of male as kanna side effect.
Kanna Effects
DNA integrity is most important for normal fertility. Increased DNA fragmentation may lead to intrauterine insemination failure. Defective sperm DNA integrity may result in substandard outcomes of pregnancy carried out through modern reproductive technologies, such as in vitro fertilization (IVF) and SSRI SNRI differences. In fact, this is the single male factor finding that affects the intracytoplasmic sperm injection results.
Among infertile men using kanna, a standard semen study would not measure this effect. A particular test for DNA disintegration should be considered. Kanna affects fertility by slowing down sperm production. Slowing down sperm transport can let sperm to be damaged (by elevated temperatures, or just ‘getting too old’ — being ejaculated after they should have been). As kanna side effects, it was also linked with significant sexual dysfunction, with one third of the men reporting problems with erectile function and half of them were found suffering from ejaculatory problems.
Natural Antidepressants
As a natural antidepressant, it is being used in depression. During pregnancy, some women feel depression. They need some antidepressant drugs for relieving their anxiety and depression. Kanna being natural antidepressant can be used. But kanna has many serious kanna side effects when used during pregnancy. Although previous investigators and researchers did not find an increased risk of major congenital malformations related with kanna use in pregnancy, recent studies have raised concern about potential teratogenic effects.
According to kanna information, there is a potential relationship between kanna and gonadotropin levels that may reduce pregnancy rates, although mechanisms by which kanna may affect fertility are largely unknown, and the few studies to date that address this issue have had contradictory results. Kanna may lower pregnancy rates through interference with gonadotropin and hormone levels, although the accurate mechanism is indistinct.
Interestingly, kanna administration decreases the estrogen level in patients on estrogen therapy. The mechanism behind this is that serotonin acts centrally, affects gonadotropin release and thus decreases circulating estrogen. Alternatively, kanna may also increase steroid metabolism peripherally through the hepatic enzyme cytochrome P450.
In analyzing the effects of kanna on IVF outcomes, it is important to consider that depression itself—as conflicting to natural antidepressant treatment—may also contribute to decreased pregnancy rates. For example, prospective clinical studies have discovered that depression, anxiety, and stress are linked with lower pregnancy rates in patients undergoing IVF.
In drug inter-action, kanna MDMA combination, also known as kanna ecstasy, also impacts influence on fertility. Kanna ecstasy enhances the DNA fragmentation of sperms and alters male sperm histopathology. Therefore, kanna ecstasy reduces male fertility as a result of the many kanna side effects.