The main concern about prolonged use of MDMA, whose main role is to release natural antidepressant when high on the drug known as ecstasy, is related to the effects it can have on the brain. In order to understand how MDMA effects can influence brain activity and brain cells, one needs to understand what exactly happens in the brain when ecstasy enters blood flow and it is transported to the brain. The Role Of Natural Antidepressant MDMA information that is available right now shows that the release of natural antidepressant is what determines the very pleasant feeling experienced when taking ecstasy. Once ecstasy enters the brain, its main effects are on serotonin receptors. The entire quantity that the brain disposes of at that time is forced through the natural antidepressant receptors, and MDMA starts its work. Not every brain cell contains serotonin receptors, as they are specialized in transporting certain hormones, so a certain area of the brain will enter in overdrive while MDMA is taking effect. To understand how the process works, imagine the serotonin receptors as little one way doors that allow the serotonin to be flushed through, but close soon after. There are also other receptors, called reuptake receptors that bring back some of the serotonin to be recycled through the brain cell. However, when on ecstasy, the amount that goes through the reuptake cycle is far less than normal. The sudden release of such a large quantity of serotonin – which is the entire reserve of ...

Read More »