As early as 1950 there was a link between mood disorders induced by certain drugs.  Illicit drugs were the chief cause of substance induced depression. Some of the over the counter drugs have also contributed to this depressive mood disorder. Drug Abuse Drug abuse accelerates depression in people who already have a history of depressive disorders like dysthymia (an illness which causes low levels of depression), or bipolar disorder.) Taking medicines like IFN Alpha corticosteroids, Digoxin and antidepressants are some causes for substance induced depression as noted in some myths about depression.  Some medicines like beta blockers, sedatives, Finasteride, calcium channel blockers may have a mild effect on moods and are not considered a major causes of substance induced depression. Substance Induced Depression Diagnosis However the patient’s medical history must be evaluated, before making conclusions. Generally in substance induced depression, symptoms like fatigue sleep changes, gastric problems etc. can manifest. These reactions can also be temporary and can reverse once the medicine is withdrawn.  If the patient is on drug abuse a urine sample will reveal the truth. If the mood disorder is due to taking medicines the thyroid test, Liver function test, electrolytes tests and blood urea tests will help in treating or withdrawal of the drug. Causes of Substance induced depression may include alcohol addiction. Generally addiction is a chronic disorder and the addicted person is well aware of the consequences and yet continues the addictive behavior. Alcoholism An alcoholic craves for drinks morning to evening. He gets ...

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