All of us know that excess or shortage of everything is dangerous. When things are under control, they work at an optimum level. Nature follows the rules of balance. Broken balance leads to disaster. Similarly, our body is working in a balanced way. When one of its components loses the balance, can depression cause anger it tries its best to return that component to the normal levels.  In the same way, Sam-E (S-Adenosyl Methionine) works as a co-factor in our body in a controlled manner. According to the sam-E information, it is involved in various reactions of our body. It donates its methyl group during many metabolic reactions and produces neurotransmitters (dopamine) and many other substances (creatine, carnitine, DNA, tRNA) in the body. Sam-E Information As per sam-E information, sam-E helps depression and bad moods working as a natural antidepressant. Though this natural antidepressant benefits our body in several ways, excess of this substance may aggravate some abnormal conditions of the body and depression causes. If a patient is susceptible to suffer from atherosclerosis, he/she must avoid sam-E, as it can enhance the process of atherosclerosis. Actually, when Sam-E donates its methyl group, it is converted to homocysteine. Vitamins Homocysteine with the help of vitamins (e.g. vitamin B12, vitamin B6 and folic acid) is converted back to methionine, SAM-e, glutathione and other beneficial substances. Thus, if the levels of vitamins in the body are low, homocysteine will accumulate to a harmful level in the body and may cause heart attack, stroke ...

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